ABSTRACT Background: In neurosurgery, the integrity of the dura is very important for brain surgery subjects, and the meningeal repair material play an important role in the reconstruction of the dura integrity, protection of brain tissue, and the prevention of complications such as cerebrospinal fluid leakage, intracranial infection, encephalocele, epilepsy, etc. Brain trauma, brain [...]

ABSTRACT Background Dural repair products are evolving from animal tissue derived materials to synthetic materials as well as from inert to absorbable features. Biomimicry inspired design will significantly improve growth and regeneration of dural cells and tissues for better repair effects and less complications. We have firstly developed the new absorbable Poly-Llactide (PLLA) dural [...]

The expanded endonasal approach provides access to the entire ventral skull base for resection of neoplasms involving the skull base and brain. The creation of large defects of the bone and dura endoscopically presents unique reconstructive challenges. A layered reconstruction of the dura with inlay and onlay fascial grafts covered with fat grafts is [...]

OBJECTIVE: The need to repair dural defects has prompted the use of dura mater substitutes. Many synthetic materials have been used for dural closure. Neuro-Patch (B. Braun Médical S.A., Boulogne, France) is a nonabsorbable microporous fleece composed of polyester urethane that has been approved for human use by the European Union since 1995. To [...]