A Multi-center, Randomized, Single-blind Clinical Trial of a Novel Regenerative Synthetic Absorbable Dural Repair Patch

ABSTRACT Background: In neurosurgery, the integrity of the dura is very important for brain surgery subjects, and the meningeal repair material play an important role in the reconstruction of the dura integrity, protection of brain tissue, and the prevention of complications such as cerebrospinal fluid leakage, intracranial infection, encephalocele, epilepsy, etc. Brain trauma, brain [...]

2020-08-23T13:48:44+04:3023rd August, 2020|Medprin, Redura|0 Comments

A New Biomimetic Synthetic Absorbable Dural Substitute

ABSTRACT Background Dural repair products are evolving from animal tissue derived materials to synthetic materials as well as from inert to absorbable features. Biomimicry inspired design will significantly improve growth and regeneration of dural cells and tissues for better repair effects and less complications. We have firstly developed the new absorbable Poly-Llactide (PLLA) dural [...]

2020-08-23T13:36:17+04:3023rd August, 2020|Medprin, Redura|0 Comments

Endoscopic Reconstruction of Cranial Base Defects following Endonasal Skull Base Surgery

The expanded endonasal approach provides access to the entire ventral skull base for resection of neoplasms involving the skull base and brain. The creation of large defects of the bone and dura endoscopically presents unique reconstructive challenges. A layered reconstruction of the dura with inlay and onlay fascial grafts covered with fat grafts is [...]

2020-08-23T13:27:24+04:3023rd August, 2020|Medprin, Redura|0 Comments

Repair of the Dura Mater With Processed Collagen Devices

Abstract Background: We evaluated in a canine duraplasty model how specific differences in device physicomechanical properties, porosity, and crosslinking influenced the biological performance of three processed collagen dural substitutes. Methods: Three collagen dural substitutes were studied: Dura-Guard, DuraGen, and Durepair. The initial strength, stiffness, and suture retention force were measured using standard mechanical test [...]

2020-08-23T13:16:38+04:3023rd August, 2020|Medprin|0 Comments

COMPARISON OF DEEP WOUND INFECTION RATES USING A SYNTHETIC DURAL SUBSTITUTE (NEUROPATCH) OR PERICRANIUM GRAFT FOR DURAL CLOSURE: A CLINICAL REVIEW OF 1 YEAR

OBJECTIVE: The need to repair dural defects has prompted the use of dura mater substitutes. Many synthetic materials have been used for dural closure. Neuro-Patch (B. Braun M├ędical S.A., Boulogne, France) is a nonabsorbable microporous fleece composed of polyester urethane that has been approved for human use by the European Union since 1995. To [...]

2020-08-23T13:01:16+04:3023rd August, 2020|Medprin, Redura|0 Comments

Nanofibrous Synthetic Dural Patch for Skull Base Defects: Preliminary Experience for Reconstruction after Extended Endonasal Approaches

Setting One of the consequences of the widespread use of endoscopic endonasal approaches (EEA) to skull base pathologies is the management of complex skull base defects. Nowadays, the gold standard is a multilayer closure that reproduces the physiological tissue barriers. Several techniques have been described in the literature; however, skull base reconstruction after EEA [...]

2020-08-23T12:17:18+04:3023rd August, 2020|Medprin|0 Comments
Go to Top