The Description of Oxiplex

Oxiplex is a flowable gel. The gel is a strile and absorable combination of polyethylen oxide (PEO) and sodium carboxy methylcellulose (CMC) calcium chloride and sodiuom chloride are added for stability oxiplex is non-pyrogenic. Download Article

2020-08-20T11:30:38+04:3020th August, 2020|Oxiplex|0 Comments

Clinical Study Detail on FzioMed’s adhesion barrier gel for spine surgery (available under the brand names Oxiplex®, Oxiplex®/SP and MediShield™).

Results provided are from a prospective, multi-center, randomized, third-party blinded, parallel group 352-patient U.S. pivotal clinical study comparing Oxiplex-treated patients (n=177) to surgery only patients (n=175), to assess the safety and effectiveness of Oxiplex spine gel to reduce postsurgical pain in patients undergoing their first single-level laminotomy, laminectomy, or discectomy at L4-L5 or L5-S1. [...]

2020-08-20T10:45:31+04:3020th August, 2020|Oxiplex|0 Comments

Oxiplex Reduces Leg Pain, Back Pain, and Associated Symptoms After Lumbar Discectomy

Study Design. Prospective, randomized, blinded clinical trial. Objective. To evaluate effectiveness of Oxiplex gel for reduction of pain and associated symptoms after lumbar discectomy. Summary of Background Data. Oxiplex gel (carboxymethylcellulose, polyethylene oxide, and calcium) is used during discectomy to coat the surgical site for reduction of pain and symptoms after lumbar discectomy. Methods. Patients [...]

2020-08-20T10:02:53+04:3020th August, 2020|Oxiplex|0 Comments

Safety of carboxymethylcellulose/polyethylene oxide for the prevention of adhesions in lumbar disc herniation – consecutive case series review

Background: Epidural fibrosis is regarded as a cause of failed back surgery syndrome (FBSS) when excessive adhesional/fibrotic scar tissue causes compression, pain or discomfort by tethering of nerve tissue to the surrounding muscle or bone. Fibrosis inhibitors could therefore increase the success rate of spinal surgery and decrease the need for reoperations. In recent [...]

2020-08-20T09:14:16+04:3020th August, 2020|Oxiplex|0 Comments

Use of Temporary Implantable Biomaterials to Reduce Leg Pain and Back Pain in Patients with Sciatica and Lumbar Disc Herniation

Abstract: The principle etiology of leg pain (sciatica) from lumbar disc herniation is mechanical compression of the nerve root. Sciatica is reduced by decompression of the herniated disc, i.e., removing mechanical compression of the nerve root. Decompression surgery typically reduces sciatica more than lumbar back pain (LBP). Decompression surgery reduces mechanical compression of the [...]

2020-08-20T09:04:21+04:3020th August, 2020|Oxiplex|0 Comments

Oxiplex Intraoperative Gel: An Adjuvant to Lumbar Disc surgery for the Reduction of Post-Surgical Pain

Purpose: Post-operative pain following standard lumbar discectomy can be a significant source of morbidity. We performed a prospective, randomized, blinded, parallel group clinical study of 352 patients (Oxiplex treated, N = 177 and surgery only, N = 175) to assess the safety and reduction of neurological sequelae using Oxiplex intraoperative surgical gel (FzioMed, San [...]

2020-08-20T08:48:51+04:3020th August, 2020|Oxiplex|0 Comments

Oxiplex Reduces the Incidence of Back Pain, Leg Pain, and Associated Symptoms 6 Months Following Single Level Lumbar Laminectomy for Removal of a Herniated Disc

Background: Oxiplex gel (carboxymethylcellulose, polyethylene oxide and calcium) was developed to coat and protect nerve roots for reduction of pain and symptoms following lumbar disc surgery. Purpose: To evaluate the safety and effectiveness of Oxiplex gel for reduction of pain and associated symptoms following lumbar disc surgery. Study Design: The study was a randomized, [...]

2020-08-20T08:47:55+04:3020th August, 2020|Oxiplex|0 Comments

Multicenter Clinical Study Evaluating Oxiplex in Lumbar Surgery

Introduction: This study was a randomized, third-party blinded, multicenter, pivotal clinical trial to evaluate the safety and effectiveness of Oxiplex gel to reduce postoperative back and leg pain as well as related symptoms following surgery at L4-L5 or L5-S1. Methods: Subjects undergoing single-level lumbar laminectomy or laminotomy, with decompression and/or a discectomy were randomized [...]

2020-08-19T14:43:24+04:3019th August, 2020|Oxiplex|0 Comments

Use of Carboxymethylcellulose/Polyethylene Oxide Gel in Microdiscectomy With lnterlaminectomy A Case Series Comparison With Long-term Follow-up

Study Design. A consecutive, case series comparison. Objective. To compare safety, long-term pain, and disability scores with and without use of carboxymethylcellulose/polyethylene oxide (CMClPEO) gel after microdiscectomy with interlaminectomy. Summary of Background Data. Patient outcomes after microdiscectomy for lumbar disc herniation are frequently complicated by adhesions and fibrotic scars. Present management is controlled by [...]

2020-08-19T14:32:39+04:3019th August, 2020|Oxiplex|0 Comments
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